GLP-1 Core
Great for first‑time users
Limited-Time Offer: $100 OFF select plans. Use code SUMMER100 at checkout.
Two signals, one shot – combines GLP-1 and GIP receptor activation for broader appetite & glucose control. Ideal for patients needing extra glucose control or stronger appetite modulation for greater weight-loss goals.
*Payable up front with a 12-month plan, if prescribed. Prescription products require an online consultation with a healthcare professional who will determine if a prescription is appropriate. This formulation is available only through prescription for patients with a demonstrated clinical need.
This compounded formulation is not FDA-approved and is intended solely for patients under active care of a licensed prescriber. It is compounded in accordance with federal Section 503A guidelines.
Experience the enhanced effects of dual receptor activation for superior metabolic outcomes.
Compared to Single Receptor GLP-1 Core
Superior glucose management through dual receptor activation
Improvements in fasting glucose, HbA1c, triglycerides, and blood pressure
Complete treatment delivered to your door with ongoing support
A quick, visual comparison of Core, Advanced, and Elite to guide your selection.
Great for first‑time users
Your current selection
Maximum support and results
Advanced dual-receptor targeting that combines powerful GLP-1 and GIP activation for maximum metabolic impact.
Slows gastric emptying, curbs appetite, and improves post-meal glucose disposal.
Amplifies insulin response and satiety while preserving lean mass.
Complementary effects of simultaneous GLP-1 and GIP activity on beta-cell function and appetite regulation.
Our streamlined process gets you matched with the perfect program quickly and safely.
Experience the difference of personalized, accessible healthcare
Work with licensed medical providers who understand your body and goals.
No hidden fees or surprise charges. Just clear, honest pricing from day one.
Get access to your care team, whenever you need it. From questions to progress check-in.
“Enhance.MD was amazing to work with. Their providers, to the nutritionist to customer service, were all super helpful and professional.”
Sherri S.
Verified Patient
Oct 5, 2024
“Being a first time subscriber, there were many choices... their follow up, professionalism, and pricing seemed to backup their claims.”
Scott Hallstrom
Verified Patient
Sep 26, 2024
“The process took slightly longer than I expected but communication back was timely and clear. Got my medication and already seeing benefits.”
Alyssa Wells
Verified Patient
Sep 16, 2024
“Enhance.MD was amazing to work with. Their providers, to the nutritionist to customer service, were all super helpful and professional.”
Sherri S.
Verified Patient
Oct 5, 2024
“Being a first time subscriber, there were many choices... their follow up, professionalism, and pricing seemed to backup their claims.”
Scott Hallstrom
Verified Patient
Sep 26, 2024
“The process took slightly longer than I expected but communication back was timely and clear. Got my medication and already seeing benefits.”
Alyssa Wells
Verified Patient
Sep 16, 2024
Everything you need to know about GLP-1 + GIP Advanced
GLP-1 Advanced combines dual receptor activation for enhanced metabolic benefits. While GLP-1 Core focuses on single receptor activation, the Advanced formula adds GIP receptor activation for broader insulin and satiety signaling, making it ideal for patients who need stronger appetite modulation or have plateaued on single-receptor medications.
Most patients begin to see initial results within 2-4 weeks, with significant weight loss typically occurring within the first 3 months. The dual-action formula often produces faster results compared to single-receptor medications.
Common side effects may include nausea, decreased appetite, and mild gastrointestinal discomfort, which typically subside as your body adjusts. Our medical team will work with you to manage any side effects through dosage adjustments and supportive care.
GLP-1 Advanced is ideal for patients who need extra glucose control, stronger appetite modulation, or have plateaued on other GLP-1 medications. Our medical team will evaluate your health history and goals to determine if this is the right option for you.
Your subscription includes 4 weeks of medication, ongoing provider care and support, metabolic lab testing every 6 months, essential supplies (syringes and alcohol pads), wellness coaching, and full platform access with educational content.
Have more questions? We're here to help.
If at any point during the onboarding process you are found ineligible for our formulation, Enhance.MD will provide a full refund of 100% of your initial payment.